Blood flow in vessels, if developing blockage, causes cells to respond by enlarging the vessel, or creating turbulence. This appears to be a built-in mechanism, not an IM invention:-http://medicalxpress.com/news/2014-12-cell-division-tissue.html-"'This is a strong result, that both the experimental results and simulations say that increased cell division may help tissue to grow and heal in a beneficial way and that this process is based exclusively on a physically-dependent diffusion, requiring no biological signalling. This may be important for healing around blood clots - and it is an example of nature's ingenious ability to take care of itself," explains Lene Oddershede."