The complexity of enzymes that control cell construction is amazing. How did they develop?-"The new structure provides crucial information for understanding how the protein binds to cellular components. It's also the first structure determined of any ligase in the tubulin tyrosine ligase-like (TTLL) family.-"Scientists have been especially curious about the role of TTLLs because mutations in these proteins have been linked to a range of neurodegenerative diseases, including retinal dystrophy and the rare Joubert syndrome.-"'This protein is highly expressed in the nervous system and has an integral role in neuronal development," said Elizabeth Wilson-Kubalek, senior staff scientist in Professor Ron Milligan's laboratory at TSRI." - Read more at: http://phys.org/news/2015-05-enzyme-important-nervous-health.html#jCp