Overwhelming complexity:-http://www.the-scientist.com//?articles.view/articleNo/41605/title/Big-Data-and-the-Brain/-"Given the organ's complexities at nearly every level of organization, he said, tracking the cellular components of the brain poses unique challenges. For one, the brain is highly compartmentalized, so samples from different regions will likely yield neurons that perform different functions. Moreover, when examining even the smallest tissue samples, there is “a massive amount of communication going on” among nerve cells, said Lichtman. “Each cell is dealing with thousands of inputs and thousands of outputs.”"