In the past I have alluded to the use of information theory, that is, looking at some functionality and determining the number of information 'bits' necessary to create function or organ functionality, or the origin itself. That terrible website (in George's view)Uncommon Descent has today a video that discusses a math approach to the issue of origin of life, natural/chance or intelligently guided, by a Ph.D. candidate at the U. of Guelph: http://www.uncommondescent.com/