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> The discovery of this system wins the Nobel. it must develop using the brain&apos;s plasticity ability:-http://www.the-scientist.com//?articles.view/articleNo/41155/title/Brain-s--Inner-GPS--Wins-Nobel/-"Together identifying an inner positioning system within the brain, O&apos;Keefe is being honored for his discovery of so-called place cells, while the Mosers are recognized for their later work identifying grid cells.   &#147;The discoveries of John O&apos;Keefe, May-Britt Moser and Edvard Moser have solved a problem that has occupied philosophers and scientists for centuries,&#148; the Nobel Foundation noted in its press release announcing the award: &#147;How does the brain create a map of the space surrounding us and how can we navigate our way through a complex environment?&#148;-Another take: http://www.washingtonpost.com/news/morning-mix/wp/2014/10/06/three-who-discovered-inner-gps-win-nobel-prize-in-medicine/-"In 2005, the Mosers mapped the connections in the hippocampus as rats moved about a room. They &#147;discovered an astonishing pattern of activity in a nearby part of the brain called the entorhinal cortex,&#148; where certain cells activated as the rats moved past locations in a hexagonal grid.   "The found that these &#147;grid cells&#148; comprised a system of coordinates that permitted spatial navigation.   "Later research using brain imaging showed that the same system exists in humans. Patients with Alzheimer&apos;s disease lose their way around because the particular areas of the brain are affected."